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當(dāng)前位置：首頁 > 產(chǎn)品展示 > Peprotech細(xì)胞因子 > 樹突狀細(xì)胞研究相關(guān)蛋白 > Recombinant Human G-CSF

名稱	Recombinant Human G-CSF
型號(hào)
更新時(shí)間	2023-09-24
特點(diǎn)	g - csf的造血生長因子刺激承諾祖細(xì)胞中性粒細(xì)胞的發(fā)展和增強(qiáng)的功能活動(dòng)end-cell成熟。產(chǎn)生針對(duì)特定的刺激多種細(xì)胞包括巨噬細(xì)胞、成纖維細(xì)胞、內(nèi)皮細(xì)胞和骨髓基質(zhì)。使用g - csf臨床上促進(jìn)骨髓移植后造血恢復(fù)。}

詳細(xì)內(nèi)容

一.產(chǎn)品名稱：Recombinant Human G-CSF

二.Catalog Number:300-23

Synonyms:

Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin

Description:

G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.

AA Sequence:

TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIW MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

Cross Reactivity:

Monkey, Mouse, Pig, Human, Plant