| 名稱 | Recombinant Human IGF-I |
| 型號(hào) | |
| 更新時(shí)間 | 2023-09-24 |
| 特點(diǎn) | IGFs促有絲分裂的多肽生長(zhǎng)因子,刺激增殖和生存的各種細(xì)胞類型包括肌肉、骨骼和軟骨組織體外。IGFs主要是由肝臟產(chǎn)生,盡管各種組織產(chǎn)生IGFs*的時(shí)候。IGFs屬于胰島素基因家族,還包含胰島素和松弛素。胰島素IGFs相似的結(jié)構(gòu)和功能,但有更高的比胰島素刺激經(jīng)濟(jì)活動(dòng)。} |
產(chǎn)品展示 / PRODUCTS
- 詳細(xì)內(nèi)容
一.產(chǎn)品名稱：Recombinant Human IGF-I /Peprotech IGF-1
二.Catalog Number:AF-100-11
三.Synonyms:Insulin-like Growth Factor-I, Somatamedin C, IGF-IA
四.Description:
The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. Manufactured using all non-animal reagents.
五.AA Sequence:
GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
六.Source:E.coli
七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:
The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
九.Cross Reactivity:
Bacteria, Chicken, Cow, Frog, Horse, Monkey, Mouse, Pig, Rat, Sheep, Tiger Salamander, Human, N/A
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電話/傳真：13366128764
手機(jī)：15311648455
地址：北京市海淀區(qū)廂黃旗2號(hào)樓1層4-179室